Article

Genetic Testing of Fetal Loss of Heterozygosity Using Single Nucleotide Polymorphism Array and Whole Exome Sequencing

2023-08-01

Abstract excerpt

<h4>Background: </h4> To explore the clinical significance of fetal loss of heterozygosity (LOH), identified by single-nucleotide polymorphism array (SNP array). <h4>Methods: </h4> We retrospectively reviewed data form pregnant women who underwent invasivediagnostic procedure at prenatal diagnosis centers in Southeastern China from December 2016 to December 2021. SNP array was performed by the Affymetrix CytoScan...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56dc5f84-912d-5289-89ee-b280b19e4f06
DOI: 10.21203/rs.3.rs-3137002/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic Testing of Fetal Loss of Heterozygosity Using Single Nucleotide Polymorphism Array and Whole Exome SequencingDOI 10.21203/rs.3.rs-3137002/v1Read

Genetic testing for fetal loss of heterozygosity using single nucleotide polymorphism array and whole-exome sequencing.Semantic proximity Read

Absence of heterozygosity detected by single-nucleotide polymorphism array in prenatal diagnosis.Semantic proximity Read

Prenatal Whole-Genome Sequencing for Fetal Anomalies: Diagnostic Performance, Challenges, and Clinical Implications.Semantic proximity Read

Utility of trio‐based prenatal exome sequencing incorporating splice‐site and mitochondrial genome assessment in pregnancies with fetal ultrasound anomalies: prospective cohort studySemantic proximity Read

Low-pass genome sequencing reveals associations between copy number variations and fetal ultrasonographic anomalies and soft markers in a cohort of 43,721 fetusesSemantic proximity Read

Prenatal diagnosis of fetuses with region of homozygosity detected by single nucleotide polymorphism array: a retrospective cohort study.Semantic proximity Read

Genetic Analysis of Isolated Fetal Growth RestrictionSemantic proximity Read

Whole-exome Sequencing in deceased fetuses with ultrasound anomalies: A Retrospective AnalysisSemantic proximity Read

Clinical utility of chromosomal microarray analysis and whole exome sequencing in fetuses with oligohydramniosSemantic proximity Read

Clinical utility of trio whole exome sequencing in fetuses with ultrasound anomaliesSemantic proximity Read

Trio exome sequencing is highly relevant in prenatal diagnosticsSemantic proximity Read

Exome sequencing in every pregnancy? Results of trio exome sequencing in structurally normal fetusesSemantic proximity Read