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Article

Genetic testing for fetal loss of heterozygosity using single nucleotide polymorphism array and whole-exome sequencing.

Scientific reports - 25 Jan 2024

Xue Huili, Yu Aili, Zhang Lin, Chen Lingji, Guo Qun, Lin Min, Lin Na, Chen Xuemei, Xu Liangpu, Huang Hailong

Abstract excerpt

The study explored the clinical significance of fetal loss of heterozygosity (LOH) identified by single-nucleotide polymorphism array (SNP array). We retrospectively reviewed data from pregnant women who underwent invasive diagnostic procedures at prenatal diagnosis centers in southeastern China from December 2016 to December 2021. SNP array was performed by the Affymetrix CytoScan 750 K array platform. Fetuses...

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Identifiers

PMID: 38273042
DOI: 10.1038/s41598-024-52812-y
PMCID: PMC10810965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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