Article

Title of the manuscript: Lynch-like syndrome with germline WRN mutation in Bulgarian patient with synchronous endometrial and ovarian cancer

2023-01-06

Abstract excerpt

<h4>Background: </h4> Synchronous endometrial and ovarian cancer (SEOC) accounts for 50-70% of all synchronous gynecology cancers in women. Approximately 14% of SEOC cases are caused by Lynch syndrome (LS). The widespread introduction of "universal screening" at LS (all cases with CRC and all EC cases diagnosed before age 60 should be tested for MMR deficiency) has led to an increasing number of suspected LS cases...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 564fd65e-ef3f-52f7-b1e7-40825630dfcd
DOI: 10.21203/rs.3.rs-2430613/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Title of the manuscript: Lynch-like syndrome with germline WRN mutation in Bulgarian patient with synchronous endometrial and ovarian cancerDOI 10.21203/rs.3.rs-2430613/v1Read

Hereditary Endometrial Cancer: Lynch Syndrome, Mismatch Repair Deficiency, and Emerging Genetic Predispositions-A Comprehensive Review with Clinical and Laboratory Guidelines.Semantic proximity Read

Gynaecological neoplasms in common familial syndromes (Lynch and HBOC).Semantic proximity Read

Universal screening for Lynch syndrome in endometrial cancers: frequency of germline mutations and identification of patients with Lynch-like syndrome.Semantic proximity Read

Clinicopathological Analysis and Literature Review of Four Cases of Lynch-like SyndromeSemantic proximity Read

Evaluation of a nationwide Dutch guideline to detect Lynch syndrome in patients with endometrial cancer.Semantic proximity Read

Clinicopathologic features of endometrial cancer with mismatch repair deficiencySemantic proximity Read

Identification of novel pathogenic MSH2 mutation and new DNA repair genes variants: investigation of a Tunisian Lynch syndrome family with discordant twinsSemantic proximity Read

Epidemiological analysis of hereditary endometrial cancer in a large study population.Semantic proximity Read

Molecular Genetics and Clinical-Pathology Features of Hereditary Nonpolyposis Colorectal Carcinoma (Lynch Syndrome)Semantic proximity Read

Mismatch Repair Universal Screening of Endometrial Cancers (MUSE) in a Canadian CohortSemantic proximity Read

[Lynch syndrome and gynaecologic's cancer: follow-up recommendations].Semantic proximity Read

Endometrial and ovarian cancer in women with Lynch syndrome: update in screening and prevention.Semantic proximity Read