Article

Predictive Performance and Clinical Application of COV50, A Urinary Proteomic Biomarker in Early COVID-19 Infection: A Cohort Study

2022-01-25

Abstract excerpt

Background: The SARS‑CoV‑2 pandemic remains a worldwide challenge. The CRIT‑Cov‑U pilot study generated a urinary proteomic biomarker consisting of 50 peptides (COV50), which predicted death and disease progression. Following the interim analysis demanded by the German government, the full dataset was analysed to consolidate findings and propose clinical applications. <br><br>Methods: In eight European countries...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56124ffd-7de5-521f-8eff-7fb14ed04e27
DOI: 10.2139/ssrn.4006139

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predictive Performance and Clinical Application of COV50, A Urinary Proteomic Biomarker in Early COVID-19 Infection: A Cohort StudyDOI 10.2139/ssrn.4006139Read

Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a cohort studySemantic proximity Read

Urinary peptides predict future deathSemantic proximity Read

Predicting COVID-19 Patients Outcome Trajectories Using Proteomics and Clinical Biosignatures: A Comprehensive Machine Learning and Bioinformatics ApproachSemantic proximity Read

International Comparisons of Harmonized Laboratory Value Trajectories to Predict Severe COVID-19: Leveraging the 4CE Collaborative Across 342 Hospitals and 6 Countries: A Retrospective Cohort StudySemantic proximity Read

Diagnostic Performance of a Blood Urea Nitrogen to Creatinine Ratio-Based Nomogram for Predicting in-Hospital Mortality in COVID-19 PatientsSemantic proximity Read

Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19Semantic proximity Read

SGLT2-Inhibition reverts urinary peptide changes associated with severe COVID-19: an<i>in-silico</i>proof-of-principle of proteomics-based drug repurposingSemantic proximity Read

Urinary collagen peptides predict mortalitySemantic proximity Read

A Prognostic Tool for COVID-19 Decision Support: The Intermountain Risk Score Predicts Major Adverse Health Events in Patients Positive for COVID-19Semantic proximity Read

Multiomics Evaluation of Gastrointestinal and Other Clinical Characteristics of COVID-19.Semantic proximity Read

Using Automated-Machine Learning to Predict COVID-19 Patient Survival: Identify Influential BiomarkersSemantic proximity Read

Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomicsSemantic proximity Read