What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality

Abstract excerpt

<h4>Key Points</h4> <h4>Question</h4> What is the role of body mass index, systolic blood pressure and smoking in mediating the effect of education on cardiovascular disease risk? <h4>Finding</h4> We find consistent evidence that body mass index, systolic blood pressure and smoking mediate the effect of education, explaining up to 18%, 27% and 33% respectively. Including all three risk factors in a model togeth...

Topics

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• Educational Status
• Genome-Wide Association Study
• Health disparities and outcomes
• Hypertension
• Mendelian Randomization Analysis
• Polymorphism, Single Nucleotide
• Risk Factors
• Stroke

Identifiers and source

Literature Corpus work

55f0cc2d-3549-5883-a080-c4c2a9196859

DOI

10.1101/488254