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Article

Educational attainment as a modifier for the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank.

International journal of epidemiology - 13 Jun 2022

Carter Alice R, Harrison Sean, Gill Dipender, Davey Smith George, Taylor Amy E, Howe Laura D, Davies Neil M

Abstract excerpt

BACKGROUND: Understanding the interplay between educational attainment and genetic predictors of cardiovascular risk may improve our understanding of the aetiology of educational inequalities in cardiovascular disease. METHODS: In up to 320 120 UK Biobank participants of White British ancestry (mean age = 57 years, female 54%), we created polygenic scores for nine cardiovascular risk factors or diseases: alcohol...

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Identifiers

PMID: 35134953
DOI: 10.1093/ije/dyac002
PMCID: PMC9189971

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