Article

Agreement between mega-trials and smaller trials: a meta-research study

2024-05-09

Abstract excerpt

Importance: Mega-trials can provide large-scale evidence on important questions. <h4>Objective:</h4> To explore how the results of mega-trails compare to the meta-analysis results of trials with smaller sample sizes. Data Sources: Clinicaltrials.gov was searched for mega-trials until 10.01.2023. PubMed was searched until June 2023 for meta-analyses incorporating the results of the eligible mega-trials. Study Selec...

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Literature Corpus work: 55e9a7b5-bc7c-5d7f-9f59-8d1ece9c5d7c
DOI: 10.1101/2024.05.09.24307122

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