Article
Protective Effect of Bacteroides fragilis on TNF-α- Induced Inflammatory Changes in Human Colon Epithelial Cells and in Inflammatory Bowel Disease Mouse Model
2023-03-08
Abstract excerpt
Bacteroides fragilis, one of the potential next-generation probiotics, but its protective mechanism is not yet known. We aimed to characterize the anti-inflammatory effect of B. fragilis and to elucidate its mechanism through in vivo and in vitro experiments. An in vitro model of inflammation by induction of colonic cells with TNF-a, and co-cultured with B. fragilis to detect cell viability, apoptosis and invasive...
Topics
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- Bacterial Identification and Susceptibility Testing
- Clostridium difficile and Clostridium perfringens research
- Digestive system and related health
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Inflammatory Bowel Disease
- Pharmacological Effects of Natural Compounds
- Probiotics and Fermented Foods
Identifiers and source
- Literature Corpus work
- 55c394bb-0f6e-5081-959a-82b73e9c9d89
- DOI
- 10.21203/rs.3.rs-2584285/v1
