Article

Subclinical Organ Dysfunction and Early Mortality Risk in Sickle Cell Disease: Integrating Biomarkers and Precision Medicine Approaches

2026-06-10

Abstract excerpt

Sickle cell disease (SCD) is a hereditary hemoglobin disorder associated with chronic hemolysis, recurrent vaso-occlusive events, progressive organ injury, and reduced life expectancy. Despite advances in supportive care and disease-modifying therapies, early mortality remains a significant concern, often driven by subclinical organ dysfunction that develops before overt clinical manifestations become apparent. Co...

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Literature Corpus work: 55381541-94df-57fd-af00-38bd4a4f1566
DOI: 10.14293/pr2199.003809.v1

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