Crucial role of telomere maintenance-related genes in survival prediction and subtype identification in colorectal cancer

Abstract excerpt

Abstract Telomere maintenance genes are closely related to colorectal cancer (CRC) development and progression. However, the potential influence of telomere maintenance-related genes (TMRGs) on the prognosis of CRC and their clinical relevance remains insufficiently explored. Utilizing mRNA expression data from the Cancer Genome Atlas (TCGA), we developed a risk model with three telomere maintenance-related biomar...

Topics

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• Epigenetics and DNA Methylation
• Genetics, Aging, and Longevity in Model Organisms
• Telomeres, Telomerase, and Senescence

Identifiers and source

Literature Corpus work

54d63322-4a60-539e-8a8f-f7f8eae60866

DOI

10.3389/fmolb.2026.1728178