Article

Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota

2021-07-19

Abstract excerpt

<h4>Objective</h4> To investigate whether axial spondyloarthritis (AxSpA) patients have an altered immunoglobulin A (IgA) response in the gut and oral microbial communities. <h4>Methods</h4> We performed 16S rRNA gene (16S) sequencing on IgA positive (IgA + ) and IgA negative (IgA − ) fractions (IgA-SEQ) from feces (n=17 AxSpA; n=14 healthy) and saliva (n=17 AxSpA; n=12 healthy), as well as on IgA-unsorted fec...

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Literature Corpus work: 54d627af-537c-5c52-863c-c0621579c408
DOI: 10.1101/2021.07.15.452558

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