Article

Diverse Roles of Tubulin Polymerization Promoting Protein 3 (TPPP3) in Human Health and Disease

2025-09-22

Abstract excerpt

The tubulin polymerization promoting proteins (TPPPs) are a small family of conserved proteins originally characterized as microtubule binding proteins. TPPP1, the first identified member, both binds to and bundles microtubules. Its homologs, TPPP2 and TPPP3, are encoded by separate genes on distinct chromosomes, but both lack the N-terminal tail present in TPPP. Functional studies revealed that TPPP3 retains comp...

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Literature Corpus work: 54d300bf-707e-55a3-bf15-c9f2303b0732
DOI: 10.20944/preprints202509.1779.v1

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