Article

Effect of doxorubicin on viability and Bax, Bcl-2, p53, Nanog, Sox-2, Oct-4 gene expressions in MCF-7 stem-like cells

2023-03-31

Abstract excerpt

<h4>Background: </h4> The aim of this study is to clarify whether cell viability, cell death, and gene expressions pertaining to self-renewal and pluripotency differ in doxorubicin (DOX) [IC 50 ] treated and untreated human MCF-7 mammalian cancer cells as well as between their CD44 + /CD24¯ /low cancer stem cells (CSC). <h4>Methods: </h4>: Non-tumorigenic human MCF-10A mammalian cells and their CD44 + /CD24¯ /low...

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Literature Corpus work: 54abf017-e32a-5b9e-ac9e-266e480b6b05
DOI: 10.21203/rs.3.rs-2677263/v1

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