Article

Gene Loss and Acquisition in Lineages of Pseudomonas aeruginosa Evolving in Cystic Fibrosis Patient Airways

2020-10-26

Abstract excerpt

Bacterial airway infections, predominantly caused by P. aeruginosa , are a major cause of mortality and morbidity of CF patients. While short insertions and deletions as well as point mutations occurring during infection are well studied, there is a lack of understanding of how gene loss and acquisition play roles in bacterial adaptation to the human airways. Here, we investigated P. aeruginosa within-host evoluti...

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Literature Corpus work: 54665ca2-fad1-519f-b25a-b81492d25a91
DOI: 10.1128/mbio.02359-20

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