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Plasmablastic Transformation of CLL/SLL: The Role of Early NGS Diagnosis and Targeted Multimodal Therapy

2025-12-09

Abstract excerpt

<h4>Background: </h4> Plasmablastic lymphoma (PBL) is a rare and highly aggressive B-cell neoplasm most often associated with immunodeficiency. Transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) into PBL is exceptionally uncommon, particularly in immunocompetent individuals. This paper describes a rare synchronous SLL-to-PBL transformation and summarizes current knowledge on synchr...

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Literature Corpus work
54333856-0de8-588a-8389-90d8741eb792
DOI
10.20944/preprints202512.0805.v1
Open publication

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