Article

Diploid telomere-to-telomere assemblies reveal hierarchical satellite architectures and heritable MHC structural diversity in macaques

2026-04-21

Abstract excerpt

<title>Abstract</title> <p>The crab-eating macaque (Macaca fascicularis), a key biomedical model, exhibits substantial inter-individual variability. However, its genomic architecture remains incompletely resolved due to extensive structural complexity and reliance on haploid reference assemblies. Here, we generated 24 diploid telomere-to-telomere (T2T) haplotypes from 12 male and female individuals representing t...

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Literature Corpus work: 52f3a6c6-81e0-554b-8e28-50658ffe67a0
DOI: 10.21203/rs.3.rs-9105354/v1

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