Article
Integrated analysis of the complete sequence of a macaque genome.
Nature - 1 Apr 2025
Zhang Shilong, Xu Ning, Fu Lianting, Yang Xiangyu, Ma Kaiyue, Li Yamei, Yang Zikun, Li Zhengtong, Feng Yu, Jiang Xinrui, Han Junmin, Hu Ruixing, Zhang Lu, Lian Da, de Gennaro Luciana, Paparella Annalisa, Ryabov Fedor, Meng Dan, He Yaoxi, Wu Dongya, Yang Chentao, Mao Yuxiang, Bian Xinyan, Lu Yong, Antonacci Francesca, Ventura Mario, Shepelev Valery A, Miga Karen H, Alexandrov Ivan A, Logsdon Glennis A, Phillippy Adam M, Su Bing, Zhang Guojie, Eichler Evan E, Lu Qing, Shi Yongyong, Sun Qiang, Mao Yafei
Abstract excerpt
The crab-eating macaques (Macaca fascicularis) and rhesus macaques (Macaca mulatta) are pivotal in biomedical and evolutionary research1-3. However, their genomic complexity and interspecies genetic differences remain unclear4. Here, we present a complete genome assembly of a crab-eating macaque, revealing 46% fewer segmental duplications and 3.83 times longer centromeres than those of humans5,6. We also...
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