Article

A unified evolutionary framework to reconstruct the viral histories of human, simian, and prosimian immunodeficiency viruses across timescales

2023-06-28

Abstract excerpt

The evolutionary history of simian and prosimian immunodeficiency viruses (SIVs and pSIVs) remains difficult to resolve due to time-dependent rate variation in viral evolution. Standard molecular clock methods relying on contemporary sequences often underestimate viral ages, conflicting with paleovirological and biogeographical evidence. Here, we apply the Prisoner of War model, which accounts for time-dependent r...

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Literature Corpus work: 5274706f-7cd1-5842-9fd7-4ae34cbd28a0
DOI: 10.1101/2023.06.28.546833

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