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Mutational dynamics and phylogenetic insights into monkeypox virus clade I evolution.

Computational biology and chemistry - 1 Dec 2025

Loganathan Tamizhini, Vasudevan Karthick, Fletcher John, Abraham Priya, Kannangai Rajesh, Doss C George Priya

Abstract excerpt

The monkeypox virus (MPXV) has evolved from causing sporadic outbreaks to becoming a global public health threat. The re-emergence of clade I in 2023 poses a significant concern. Recently, the first case of the monkeypox clade I variant was reported in India. In this context, the proposed study examines the distinct evolutionary paths of clades I, Ia, and Ib, focusing on their genetic diversity, mutational...

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PMID: 40505262
DOI: 10.1016/j.compbiolchem.2025.108536

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