Article

Unlocking data in <i>Klebsiella</i> lysogens to predict capsular type-specificity of phage depolymerases

2024-07-25

Abstract excerpt

Viral entry is a critical step in the infection process. Klebsiella spp. and other clinically relevant bacteria often express a complex polysaccharide capsule that acts as a barrier to phage entry. In turn, most Klebsiella phages encode depolymerases for capsule removal. This virus-host arms race has led to extensive genetic diversity in both capsules and depolymerases, complicating our ability to understand the...

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Literature Corpus work: 52340bb5-6ec2-5521-8c4f-132335578381
DOI: 10.1101/2024.07.24.604748

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