Article

Gallocin A, an atypical two-peptide bacteriocin with intramolecular disulfide bonds required for activity

2022-12-08

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus gallolyticus subsp. gallolyticus ( SGG ) is an opportunistic gut pathogen associated with colorectal cancer. We previously showed that colonization of the murine colon by SGG in tumoral conditions was strongly enhanced by the production of gallocin A, a two-peptide bacteriocin. Here, we aimed at characterizing the mechanisms of its action and resistance. Using a genetic approach...

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Literature Corpus work: 50efacde-16c3-5537-b3c4-89dc6ae03fe7
DOI: 10.1101/2022.12.05.519244

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