Article

Trametinib Monotherapy for the Treatment of Brain Metastasis from NSCLC: A Case Report and Literature Review

2021-05-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold>BRAF mutation mostly was observed in lung adenocarcinoma, accounting for about 4.9%. It mainly including V600E mutation and other rare mutations, among which non-V600E positive accounted for about 43.3%.<bold>Case presentation:</bold>We report a case that postoperative recurrence NSCLC with brain metastasis and multiple lymph nodes metastasis, who had been develo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5050f200-0b4a-54b6-8755-023f99f73bf1
DOI: 10.21203/rs.3.rs-484320/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Trametinib Monotherapy for the Treatment of Brain Metastasis from NSCLC: A Case Report and Literature ReviewDOI 10.21203/rs.3.rs-484320/v1Read

Trametinib Monotherapy for the Treatment of Brain Metastasis From Non-small-cell Lung Cancer: a Case ReportSemantic proximity Read

A retrospective study of the efficacy and safety of Almonertinib in the treatment of locally advanced or brain metastatic non-small cell lung cancer with EGFR-positive mutationsSemantic proximity Read

Treatment of Alectinib in NSCLC with Brain Metastasis Patient Refractory to Radiotherapy after Resistance to Crizotinib: A Case Report and Literature ReviewSemantic proximity Read

[Targeted Therapies for Driver Gene Mutation-positive Lung Cancer Patients with Brain Metastasis].Semantic proximity Read

Erlotinib as a salvage treatment after gefitinib failure for advanced non-small-cell lung cancer patients with brain metastasis: A successful case report and review.Semantic proximity Read

Management and Outcomes of Newly Diagnosed Non-Small Cell Lung Cancer Patients with Brain Metastases: A Real-World Study in Japan.Semantic proximity Read

Pharmacotherapeutic options for treating brain metastases in non-small cell lung cancer.Semantic proximity Read

[Initial Treatment of Aumolertinib in Combination with Bevacizumab for Advanced NSCLC with Primary EGFR T790M Mutation: A Report of Three Cases and Literature Review].Semantic proximity Read

Commentary: Treatment Considerations for Patients With Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer Brain Metastases in the Era of Tyrosine Kinase Inhibitors.Semantic proximity Read

Icotinib is as efficacious as gefitinib for brain metastasis of EGFR mutated non-small-cell lung cancerSemantic proximity Read

Outcomes of 27 Non-Small Cell Lung Cancer Patients Receiving Resections of Paired Primary Pulmonary and Brain Metastatic Tumours: Is EGFR Negative Mutation of Brain Metastasis Bring More Benefit?Semantic proximity Read

[Clinical Features of EGFR Mutation Negative in Patients with Non-small Cell Lung Cancer and Brain Metastases].Semantic proximity Read