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Article

[Clinical Features of EGFR Mutation Negative in Patients  with Non-small Cell Lung Cancer and Brain Metastases].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Jan 2021

Zhu Yixiang, Zhang Ye

Abstract excerpt

In addition to rare incidence of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 receptor kinase (ROS1) positive patients, patients with brain metastases of non-small cell lung cancer (NSCLC) without epidermal growth factor receptor (EGFR) sensitive mutation have no effective systemic therapy at present, and the overall prognosis is poor. Since the low blood-brain barrier permeability of chemotherapy drugs,...

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Identifiers

PMID: 33478190
DOI: 10.3779/j.issn.1009-3419.2020.102.48
PMCID: PMC7849034

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