Article

Pathophysiology of voluntary motor commands at the level of the spinal motoneuron in patients with multiple sclerosis

2025-08-13

Abstract excerpt

Multiple sclerosis (MS) is a progressive inflammatory neurodegenerative disease that degrades neural transmission between the brain and spinal α-motoneurons. These voluntary motor commands contain excitatory, inhibitory, and neuromodulatory components that must be appropriately balanced for skilled motor control. Unlike other clinical populations, in MS we have no knowledge about how voluntary motor commands are d...

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Literature Corpus work: 4fca62db-cf56-5fd8-a3ab-37c3dede38c6
DOI: 10.1101/2025.08.12.25333527

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