Article
Brain state stability during working memory is explained by network control theory, modulated by dopamine D1/D2 receptor function, and diminished in schizophrenia
2019-06-23
Abstract excerpt
Dynamical brain state transitions are critical for flexible working memory but the network mechanisms are incompletely understood. Here, we show that working memory entails brain-wide switching between activity states. The stability of states relates to dopamine D1 receptor gene expression while state transitions are influenced by D2 receptor expression and pharmacological modulation. Schizophrenia patients show a...
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Identifiers and source
- Literature Corpus work
- 4f5a4bb1-6450-5be4-8965-a8bb0ac0d056
- DOI
- 10.1101/679670