Article

A new insight for the screening of potential β-lactamase inhibitors

2014-05-14

Abstract excerpt

The β-lactamase produces by Aeromonas hydrophila which enables to hydrolyze and inactivate β- lactam ring of antibiotics. The homology modeling was used to generate the 3-D model of β-lactamase by using known template 3-D structure. The stereochemical quality and torsion angle of 3-D model were validated. Total eleven effective drugs have been selected and targeted the active amino acid residues in β-lactamase. T...

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Literature Corpus work: 4f1a076b-10d8-54b9-a58a-cf4403b4c062
DOI: 10.1101/005181

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