Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma

Abstract excerpt

<h4>Background: </h4> Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression and play fundamental roles in various types of cancer. Current developments in transcriptome analyses unveiled the existence of lncRNAs; however, their functional characterization remains a challenge. Methods A bioinformatics screen was performed by integration of multiple omics data in hepatocellular carcin...

Topics

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• Cancer Mechanisms and Therapy
• Cancer-related molecular mechanisms research
• Cholangiocarcinoma and Gallbladder Cancer Studies
• Kruppel-like factors research
• RNA modifications and cancer

Identifiers and source

Literature Corpus work

4e8b01c7-226f-5a5f-9f0e-4700ff4b8317

DOI

10.21203/rs.3.rs-1623763/v2