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A blastocyst-derived <i>in vitro</i> model of the <i>human</i> chorion

2025-08-08

Abstract excerpt

<h4>SUMMARY</h4> The placenta supports the foetus by mediating nutrient and gas exchange, hormone production, and immune protection. Yet, human placental biology remains poorly understood due to limited in vitro models. The foetal part of the placenta, the chorion, consists of a trophoblast-derived layer and a mesenchymal zone containing extraembryonic mesoderm cells. Here, we show that human blastocysts can giv...

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Literature Corpus work
4e4c48ed-85ae-5273-99c4-8eace2acb2b5
DOI
10.1101/2025.08.06.668884
Open publication

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