Article

Inbreeding and resultant homozygosity across key inflammation and DNA repair genes linked to chlamydial infection in New South Wales koalas

2025-07-23

Abstract excerpt

Inbreeding and resultant homozygosity can reduce genetic diversity and increase disease susceptibility. Koalas ( Phascolarctos cinereus ) are one species suffering genomic diversity loss and inbreeding and concurrent significant disease pressure (particularly chlamydiosis). Using 259 whole genomes with a pathogen sampling regime we identify potential links between inbreeding, genome-wide variation and chlamydial...

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Literature Corpus work: 4e3033cf-367c-5f74-beb3-5f3dd086ee75
DOI: 10.1101/2025.07.22.666211

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