Article

Co-Conservation of Synaptic Gene Expression and Circuitry in Collicular Neurons

2025-01-23

Abstract excerpt

<h4>ABSTRACT</h4> The superior colliculus (SC), a midbrain sensorimotor hub, is anatomically and functionally similar across vertebrates, but how its cell types have evolved is unclear. Using single-nucleus transcriptomics, we compared the SC’s molecular and cellular organization in mice, tree shrews, and humans. Despite over 96 million years of evolutionary divergence, we identified ∼30 consensus neuronal subtyp...

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Literature Corpus work: 4dd1fd4d-4c22-5553-bbcc-cfae8118b2a9
DOI: 10.1101/2025.01.23.634521

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