Article

The role of NPC2 gene in glioma was investigated based on bioinformatics analysis

2023-12-15

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is one of the most malignant primary brain tumors in adults. The <italic>NPC</italic>2 gene (Niemann-Pick type C intracellular cholesterol transporter 2) is a protein-coding gene with a lipid recognition domain. The <italic>NPC2</italic> gene was found to be significantly increased in gliomas (LGG and GBM), and it is now thought to be a risk factor. COX analysis demon...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4d9df661-3973-503a-a62a-583c786a56ee
DOI: 10.21203/rs.3.rs-3736731/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of NPC2 gene in glioma was investigated based on bioinformatics analysisDOI 10.21203/rs.3.rs-3736731/v1Read

The role of NPC2 gene in glioma was investigated based on bioinformatics analysisSemantic proximity Read

Systematic Identification of UBE2C As a Prognostic Biomarker and Correlated with Immunosuppression and Invasiveness in GliomaSemantic proximity Read

Investigation of Candidate Genes and Mechanism Associated with Immune Cell during the Progression of Glioblastoma based on BioinformaticsSemantic proximity Read

PANX2 and brain lower grade glioma genesis: A bioinformatic analysisSemantic proximity Read

ANXA2 is correlated with the molecular features and clinical prognosis of glioma, and acts as a potential marker of immunosuppressionSemantic proximity Read

ANXA2 is Correlated With the Molecular Features and Clinical Prognosis of Glioma, and Acts as a Potential Marker of ImmunosuppressionSemantic proximity Read

RNF208 is a Biomarker Associated with Immune Infiltration in Low-Grade GliomasSemantic proximity Read

Low expression of GALNT6 gene in gliomas promotes immune infiltration and improves tumor prognosis using bioinformatics analysisSemantic proximity Read

Validation of the Functions and Prognostic Values of Synapse Associated Proteins in Lower-Grade GliomaSemantic proximity Read

CPLX2 is a novel tumor suppressor and improves the prognosis in gliomaSemantic proximity Read

Bioinformatics Analysis of C3 in Brain Low Grade Gliomas as Potential Therapeutic Target and Promoting Immune Cell InfiltrationSemantic proximity Read

CLEC19A overexpression inhibits tumor cell proliferation/migration and promotes apoptosis concomitant suppression of PI3K/AKT/NF-κB signaling pathway in Glioblastoma MultiformeSemantic proximity Read