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The role of NPC2 gene in glioma was investigated based on bioinformatics analysis

19 Aug 2024

Abstract excerpt

Glioblastoma (GBM) is one of the most malignant primary brain tumors in adults. The NPC2 gene (Niemann-Pick type C intracellular cholesterol transporter 2) is a protein-coding gene with a lipid recognition domain. The NPC2 gene was found to be significantly increased in gliomas (LGG and GBM), and it is now thought to be a risk factor. COX analysis demonstrated that NPC2 was a significant risk factor for glioma....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39160329
DOI: 10.1038/s41598-024-70221-z

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