Back to search

Article

Hexokinases 2 Promoted Cell Motility and Distant Metastasis by Elevating Fibronectin Through Akt1/p-Akt1 in Cervical Cancer Cells

2021-06-23

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Hexokinases 2 (HK2) is a member of the hexokinases, linking with malignant tumor growth and distant metastasis. However, evidence regarding the potential role of HK2 in regulating cell motility and tumor metastasis during the cervical cancer malignant progression remains limited.<bold>Methods:</bold><italic> In vitro </italic>migration and invasion assay, <itali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4c86c441-420f-560a-8175-09e502d3bc76
DOI
10.21203/rs.3.rs-624489/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Hexokinases 2 Promoted Cell Motility and Distant Metastasis by Elevating Fibronectin Through Akt1/p-Akt1 in Cervical Cancer CellsDOI 10.21203/rs.3.rs-624489/v1
The Roles of HK2 on Tumorigenesis of Cervical CancerSemantic proximity
A pan-cancer analysis of the role of hexokinase II (HK2) in human tumorsSemantic proximity
Down-Regulating Hexokinase 2 Inhibits Proliferation of Endometrial Stromal Cells Through a Noncanonical Pathway Involving Phosphorylated-STAT1 in EndometriosisSemantic proximity
CircCDKN2B-AS1 interacts with IMP3 to stabilize Hexokinase 2 mRNA and facilitate cervical squamous cellcarcinoma aerobic glycolysis progressionSemantic proximity
Hexokinase 3 dysfunction promotes tumorigenesis and immune escape by upregulating monocyte/macrophage infiltration into the clear cell renal cell carcinoma microenvironmentSemantic proximity
A pan-cancer analysis of molecular characteristics and oncogenic role of hexokinase family genes in human tumorsSemantic proximity
Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancerSemantic proximity
Involvement of FAK-ERK2 signaling pathway in CKAP2-induced proliferation and motility in cervical carcinoma cell linesSemantic proximity
Targeting hexokinase 2 increases the sensitivity of oxaliplatin by Twist1 in colorectal cancerSemantic proximity
SULF1 promotes malignancy potential of cervical cancer by activating VEGFR2/PI3K/AKT signaling pathwaySemantic proximity
The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancerSemantic proximity
Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancerSemantic proximity
Select a neighboring publication to make it the new centre.