Article

MetIDfyR, an Open-Source R Package to Decipher Small-Molecule Drugs Metabolism Through High Resolution Mass Spectrometry

2020-05-27

Abstract excerpt

After administration to humans or animals, small-molecule drugs most frequently undergo several biochemical transformations by the endogenous enzymatic machinery, called phase I and phase II metabolism. These molecular processes allow organisms to eliminate xenobiotics through modification of their chemical properties and generate metabolites. With recent advances in analytical chemistry, LC-HRMS/MS has become an...

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Literature Corpus work: 4c7e639a-adc4-5be8-a510-783856eb12e9
DOI: 10.26434/chemrxiv.12368963.v1

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