Increased and decreased superficial white matter structural connectivity in schizophrenia and bipolar disorder

Abstract excerpt

Schizophrenia (SZ) and bipolar disorder (BD) are often conceptualized as “disconnection syndromes”, with substantial evidence of abnormalities in deep white matter tracts, forming the substrates of long-range connectivity, seen in both disorders. However, the study of superficial white matter (SWM) U-shaped short-range tracts remained challenging until recently, although findings from post-mortem studies suggest t...

Topics

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• Corpus Callosum
• Diffusion Tensor Imaging
• Imaging, Three-Dimensional
• Nerve Fibers, Myelinated
• Neural Pathways
• Organ Size
• Risk Assessment
• Schizophrenia

Identifiers and source

Literature Corpus work

4c266aed-c04c-5ad7-ab65-8120dfef5371

DOI

10.1101/473686