Article

Persistent Spike antigenemia is not associated with Post-COVID condition

2025-10-30

Abstract excerpt

<h4> A bstract </h4> <h4>Objectives</h4> Spike antigenemia has been proposed as one of the potential mechanisms underlying post-COVID condition (PCC). Several studies addressing Spike antigenemia have measured both free and antibody-bound Spike employing 10 mM DTT to dissociate Spike–IgG complexes. <h4>Methods</h4> Within the ORCHESTRA project, we analysed Spike and Nucleocapsid proteins in 188 participants,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 49e0f11c-e470-5fc2-89e2-1db1e48f4478
DOI: 10.1101/2025.10.24.25338528

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Persistent Spike antigenemia is not associated with Post-COVID conditionDOI 10.1101/2025.10.24.25338528Read

COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infectionSemantic proximity Read

Molecular and Immunological Signatures of Long COVID: Implications for Diagnosis and Personalized Treatment StrategiesSemantic proximity Read

Diagnostic Classification for Long Covid Patients identifying Persistent Virus and Hyperimmune PathophysiologiesSemantic proximity Read

Reliability of Spike Gene Target Failure for ascertaining SARS-CoV-2 lineage B.1.1.7 prevalence in a hospital settingSemantic proximity Read

Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral SpikeSemantic proximity Read

D614G Spike Variant Does Not Alter IgG, IgM, or IgA Spike Seroassay PerformanceSemantic proximity Read

SARS-CoV-2 S2P spike ages through distinct states with altered immunogenicitySemantic proximity Read

Hyper Production of Anti Spike Antibodies and Rheumatological Manifestations: Coincidence or Pathogenesis?Semantic proximity Read

Spike antibodies targeting GRP78 predispose to cardiovascular complications compared to DengueSemantic proximity Read

The secretory IgA (sIgA) response in human milk against the SARS-CoV-2 Spike is highly durable and neutralizing for at least 1 year of lactation post-infectionSemantic proximity Read

Circulating Synthetic SARS-CoV-2 Spike Proteins Possibly Contribute to a Transient ACE2 Dysfunction Leading to Rare Cases of Myocarditis after COVID-19 mRNA VaccinationSemantic proximity Read

Mass-Standardised IgG Response to Fourteen SARS-CoV-2 Spike Protein variants and Antibody Subclass analysis for IgG subclasses and IgE for a Long COVID Patient CohortSemantic proximity Read