Article

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite

2022-10-14

Abstract excerpt

The complex life cycle of Plasmodium falciparum requires coordinated gene expression regulation to allow host cell invasion, transmission, and immune evasion. However, this cascade of transcripts is unlikely to be regulated by the limited number of identified parasite-specific transcription factors. Increasing evidence now suggests a major role for epigenetic mechanisms in gene expression in the parasite. In euka...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 49b42f6a-60f7-5b1b-b526-08df13a49bf6
DOI: 10.1101/2022.10.12.511630

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasiteDOI 10.1101/2022.10.12.511630Read

Strand-specific RNA sequencing in Plasmodium falciparum malaria identifies developmentally regulated long non-coding RNA and circular RNASemantic proximity Read

Epigenetic Regulation and Chromatin Remodeling in Malaria ParasitesSemantic proximity Read

A bioinformatic approach for the prediction and functional classification of <i>Toxoplasma gondii</i> long non-coding RNAsSemantic proximity Read

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imagingSemantic proximity Read

Epigenetic and Epitranscriptomic Gene Regulation in Plasmodium falciparum and How We Can Use It against MalariaSemantic proximity Read

A global transcriptional analysis of Plasmodium falciparum malaria reveals a novel family of telomere-associated lncRNAsSemantic proximity Read

A comprehensive epigenome map of Plasmodium falciparum reveals unique mechanisms of transcriptional regulation and identifies H3K36me2 as a global mark of gene suppressionSemantic proximity Read

A <i>Plasmodium falciparum</i> MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatinSemantic proximity Read

Epigenetic Variation and Regulation in Malaria ParasitesSemantic proximity Read

Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stagesSemantic proximity Read

Epigenetic regulation underlying <i>Plasmodium berghei</i> gene expression during its developmental transition from host to vectorSemantic proximity Read

Plasmodium falciparum gametocytes display global chromatin remodelling during sexual differentiationSemantic proximity Read