Article

DMOG attenuates steroid-associated endothelial progenitor cell impairment and osteonecrosis of the femoral head via regulating HIF-1α signaling pathway in rabbit

2022-06-15

Abstract excerpt

<h4>Background: </h4> Steroid-associated osteonecrosis of the femoral head (SONFH), generally caused by chronic or/and high-dose use of Glucocorticoids (GCs), has long been puzzling mankind for a long time as the most essential etiology for non-traumatic ONFH. Hypoxia inducible factor-1α (HIF-1α) is an essential transcription factor that plays a significant role in maintaining bone homeostasis. By repressing proly...

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Literature Corpus work: 49a7c27f-c787-50b5-b60b-ef9e8f3f11a4
DOI: 10.21203/rs.3.rs-1740669/v1

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