Article

Statistical challenges for inferring multiple SARS-CoV-2 spillovers with early outbreak phylodynamics

2022-10-13

Abstract excerpt

Understanding how SARS-CoV-2 entered the human population, thereby causing the COVID-19 pandemic, is one of the most urgent questions in science today. Two hypotheses are widely acknowledged as being most likely to explain the pandemic’s origin in late 2019: (i) the “natural origin” hypothesis that one or more cross-species transmissions from animals into humans occurred, most likely at the Huanan Seafood Market i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 498866a2-84f8-5ef9-bf5c-ac37e3879969
DOI: 10.1101/2022.10.10.511625

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Statistical challenges for inferring multiple SARS-CoV-2 spillovers with early outbreak phylodynamicsDOI 10.1101/2022.10.10.511625Read

The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2.Semantic proximity Read

A novel computational approach to reconstruct SARS-CoV-2 infection dynamics through the inference of unsampled sources of infectionSemantic proximity Read

An updated dataset of early SARS-CoV-2 diversity supports a wildlife market originSemantic proximity Read

Association between SARS-CoV-2 and metagenomic content of samples from the Huanan Seafood MarketSemantic proximity Read

Estimates of outbreak-specific SARS-CoV-2 epidemiological parameters from genomic dataSemantic proximity Read

SARS-CoV-2: tracing the origin, tracking the evolutionSemantic proximity Read

There is no “origin” to SARS-CoV-2Semantic proximity Read

ONE CHAIN, REPEATED SPILLOVER, OR AN UNRELATED EARLY SIGNAL?Semantic proximity Read

Retrouver les origines du SARS-CoV-2 dans les phylogénies de coronavirusSemantic proximity Read

Recently reported SARS-CoV-2 genomes suggested to be intermediate between the two early main lineages are instead likely derivedSemantic proximity Read

Witnessing Evolution of SARS-CoV-2 through Comparative Phylogenomics: The Proximate Origin is Guangdong, not WuhanSemantic proximity Read

Genomic epidemiology of the early stages of the SARS-CoV-2 outbreak in RussiaSemantic proximity Read