Article
The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2.
Science (New York, N.Y.) - 26 Aug 2022
Pekar Jonathan E, Magee Andrew, Parker Edyth, Moshiri Niema, Izhikevich Katherine, Havens Jennifer L, Gangavarapu Karthik, Malpica Serrano Lorena Mariana, Crits-Christoph Alexander, Matteson Nathaniel L, Zeller Mark, Levy Joshua I, Wang Jade C, Hughes Scott, Lee Jungmin, Park Heedo, Park Man-Seong, Ching Zi Yan Katherine, Lin Raymond Tzer Pin, Mat Isa Mohd Noor, Noor Yusuf Muhammad, Vasylyeva Tetyana I, Garry Robert F, Holmes Edward C, Rambaut Andrew, Suchard Marc A, Andersen Kristian G, Worobey Michael, Wertheim Joel O
Abstract excerpt
Understanding the circumstances that lead to pandemics is important for their prevention. We analyzed the genomic diversity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) early in the coronavirus disease 2019 (COVID-19) pandemic. We show that SARS-CoV-2 genomic diversity before February 2020 likely comprised only two distinct viral lineages, denoted "A" and "B." Phylodynamic rooting methods,...
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