Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular niche

13 Apr 2021

Abstract excerpt

STUDY QUESTION: Do phytocannabinoids (PCs) affect follicular endocannabinoid signalling and the epigenome in the surrounding granulosa cells (GCs)? SUMMARY ANSWER: Exposure to PCs increases the expression of endocannabinoid receptors and reduces DNA methylation enzyme expression and global DNA methylation in naïve GCs. WHAT IS KNOWN ALREADY: Cannabis plant derivatives, known as PCs, are used for medicinal and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cannabis and Cannabinoid Research
Share to Prenatal Substance Exposure Effects
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33954787
DOI: 10.1093/humrep/deab104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular nichePMID 33954787Read ↗

Expression of the endocannabinoid system and response to cannabinoid components by the human fetal testisSemantic proximity Read ↗

The manifold actions of endocannabinoids on female and male reproductive eventsSemantic proximity Read ↗

The Epigenetics of the Endocannabinoid SystemSemantic proximity Read ↗

(Endo)Cannabinoids and Gynaecological CancersSemantic proximity Read ↗

Cannabis use and the sperm epigenome: a budding concern?Semantic proximity Read ↗

9-Tetrahydrocannabinol inhibits cytotrophoblast cell proliferation and modulates gene transcriptionSemantic proximity Read ↗

Tetrahydrocannabinol exposure to postejaculatory sperm compromises sperm structure, function, the epigenome, and early embryo developmentSemantic proximity Read ↗

Cannabis and Paternal Epigenetic InheritanceSemantic proximity Read ↗

Endocannabinoid system and pregnancySemantic proximity Read ↗

Epigenetic mechanisms and endocannabinoid signallingSemantic proximity Read ↗

The role of endocannabinoids in gonadal function and fertility along the evolutionary axisSemantic proximity Read ↗

The Endocannabinoid System and Its Relationship to Human ReproductionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.