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Article

Identification of novel reproducible combinatorial genetic risk factors for myalgic encephalomyelitis in the DecodeME patient cohort and commonalities with long COVID.

Journal of translational medicine - 21 Apr 2026

Sardell J M, Das S, Pearson M, Kolobkov D, Malinowski A R, Fullwood L M, Sanna M, Baxter H, McLellan K, Natt M, Lamirel D, Chowdhury S, Strivens M A, Gardner S

Abstract excerpt

BACKGROUND: Myalgic encephalomyelitis (also known as ME/CFS or simply ME) has severely impacted the lives of tens of millions of people globally, but the disease currently has no accurate diagnostic tools or effective treatments. Identifying the biological causes of ME has proven challenging due to its wide range of symptoms and affected organs, and the lack of reproducible genetic associations across ME...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42015188
DOI: 10.1186/s12967-026-08167-1
PMCID: PMC13235158

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