Article

Environmental and genetic predictors of human cardiovascular ageing

2022-10-04

Abstract excerpt

<h4>ABSTRACT</h4> Cardiovascular ageing is a process that begins early in life and leads to a progressive change in structure and decline in function due to accumulated damage across diverse cell types, tissues and organs contributing to multi-morbidity. Damaging biophysical, metabolic and immunological factors exceed endogenous repair mechanisms resulting in a pro-fibrotic state, cellular senescence and end-organ...

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Literature Corpus work: 49067be2-ddaa-587a-91ca-d4144d7ee501
DOI: 10.1101/2022.10.03.22280042

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