Modeling human population separation history using physically phased genomes

Abstract excerpt

Phased haplotype sequences are a key component in many population genetic analyses since variation in haplotypes reflects the action of recombination, selection, and changes in population size. In humans, haplotypes are typically estimated from unphased sequence or genotyping data using statistical models applied to large reference panels. To assess the importance of correct haplotype phase on population history i...

Topics

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• Bayes Theorem
• Black People
• Genetics, Population
• Genome, Human
• Genotype
• Haplotypes
• Models, Genetic
• Polymorphism, Single Nucleotide

Identifiers and source

Literature Corpus work

48f0d880-8365-557d-a0cd-0597663c58fd

DOI

10.1101/008367