Article

N6-methyladenosine modification of RanGAP1 promotes colorectal cancer progression via CRABP2

2022-08-12

Abstract excerpt

<title>Abstract</title><p>Ran GTPase activating protein 1 (RanGAP1) plays an important role in a variety of diseases; however, whether it affects colorectal cancer progression(COAD) is unclear. In this study, RanGAP1 was identified as a novel downstream gene of METTL3 in COAD by m6A epitranscriptomic microarray, MeRIP-seq and label-free proteomics analyses. RIP-qPCR and Luciferase reporter explored the molecular m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 48e38791-69ac-5b88-afcd-ca41a47f039e
DOI: 10.21203/rs.3.rs-1922415/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

N6-methyladenosine modification of RanGAP1 promotes colorectal cancer progression via CRABP2DOI 10.21203/rs.3.rs-1922415/v1Read

M6A methylase related MCM3AP-AS1 promotes the progression of colorectal cancer through the miR-98/IGF2BP1 signaling axisSemantic proximity Read

Bioinformatic analysis of N6-methyladenosine, 5-methylcytosine, and N1-methyladenosine co-regulation patterns and validation of NSUN6 as a protective protein in colon cancerSemantic proximity Read

NAT10 triggers colorectal cancer progression via promoting PPAN-regulated DNA damage repairSemantic proximity Read

Identification of m6A-Related Biomarkers Associated with Prognosis of Colorectal CancerSemantic proximity Read

Prognosis and personalized treatment prediction of IGF2BP2- mediated m6A modification patterns in pancreatic cancerSemantic proximity Read

Gene Alterations of N6-Methyladenosine (m6A) Regulators in Colorectal Cancer: A TCGA Database Study.Semantic proximity Read

Evaluated the Role of N6-Methyladenosine-associated lncRNAs in Prognosis and Immune Microenvironment of Colorectal CancerSemantic proximity Read

Identification and Validation of N6-methyladenosine-related Biomarkers for Bladder Cancer: Implications for ImmunotherapySemantic proximity Read

Comprehensive analysis of m6A related gene mutation characteristics and prognosis in colorectal cancerSemantic proximity Read

Comprehensive analysis of m6A related gene mutation characteristics and prognosis in colorectal cancer.Semantic proximity Read

Aerial View of the Association between m6A-Related LncRNAs and Clinicopathological Characteristics of Pancreatic CancerSemantic proximity Read

m6A Methylation Regulators Are Predictive Biomarkers for Tumour Metastasis in Prostate CancerSemantic proximity Read