Article
Gene Alterations of N6-Methyladenosine (m6A) Regulators in Colorectal Cancer: A TCGA Database Study.
BioMed research international - 1 Jan 2020
Zhang Qian, Cai Yuping, Kurbatov Vadim, Khan Sajid A, Lu Lingeng, Zhang Yawei, Johnson Caroline H
Abstract excerpt
N6-methyladenosine (m6A) plays an important role in many cancers. However, few studies have examined the role of m6A in colorectal CRC. To examine the effect of m6A on CRC, we studied the genome of 591 CRC cases from The Cancer Genome Atlas (TCGA). The relationship between the messenger RNA (mRNA) expression, copy number variation (CNVs), and mutations of m6A "Writers," "Readers," and "Erasers," prognosis, immune...
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