Article

Determination of HLA class II risk alleles and prediction of self/non-self epitopes contributing Hashimotoˈs thyroiditis in a group of Iranian patients

2023-11-09

Abstract excerpt

One of the probable hypotheses for the onset of autoimmunity is molecular mimicry. This study aimed to determine the HLA-II risk alleles for developing Hashimotoˈs thyroiditis (HT) in order to analyze the molecular homology between candidate pathogen-derived epitopes and potentially self-antigens (TPO) based on the presence of HLA risk alleles. HLA-DRB1/-DQB1 genotyping was performed in 100 HT patients and 330 eth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 48bb3b19-2c2e-5934-aafb-ed29f7b35465
DOI: 10.21203/rs.3.rs-3558098/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Determination of HLA class II risk alleles and prediction of self/non-self epitopes contributing Hashimotoˈs thyroiditis in a group of Iranian patientsDOI 10.21203/rs.3.rs-3558098/v1Read

Determination of HLA class II risk alleles and prediction of self/non-self-epitopes contributing Hashimoto's thyroiditis in a group of Iranian patients.Semantic proximity Read

HLAs in Autoimmune Diseases: Dependable Diagnostic Biomarkers?Semantic proximity Read

Environmental factors and genetic background that interact to cause autoimmune thyroid diseaseSemantic proximity Read

[Role of HLA genetic variants in autoimmune diseases].Semantic proximity Read

Significance of HLA Haplotypes in Two Patients with Subacute Thyroiditis Triggered by mRNA-Based COVID-19 VaccineSemantic proximity Read

HLA class I-associated diseases with a suspected autoimmune etiology: HLA-B27 subtypes as a model systemSemantic proximity Read

Coronavirus-associated molecular mimicry through homology to a SARS-CoV-2 peptide could be leading to susceptibility in patients with HLA-A*02:01 and HLA-A*24:02 serotypesSemantic proximity Read

HLA alleles, especially amino-acid signatures of HLA-DPB1, might contribute to the molecular pathogenesis of early-onset autoimmune thyroid diseaseSemantic proximity Read

Cutting edge: the etiology of autoimmune thyroid diseases.Semantic proximity Read

HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults.Semantic proximity Read

A Contribution to the Conceptual Model of Occurrence of Autoimmune DiseasesSemantic proximity Read

Immunogenicity of autoantigens.Semantic proximity Read