Article

Social genomics, cognition, and well-being during the COVID-19 pandemic

2023-06-05

Abstract excerpt

<h4>INTRODUCTION</h4> Adverse psychosocial exposure is associated with increased proinflammatory gene expression and reduced type-1 interferon gene expression, a profile known as the conserved transcriptional response to adversity (CTRA). Little is known about CTRA activity in the context of cognitive impairment, although chronic inflammatory activation has been posited as one mechanism contributing to late-life c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4850e6f7-d644-574b-a0d4-d72197a6afa9
DOI: 10.1101/2023.05.31.23290618

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Social genomics, cognition, and well-being during the COVID-19 pandemicDOI 10.1101/2023.05.31.23290618Read

Chronic post-COVID neuropsychiatric symptoms persisting beyond one year from infection: a case-control study and network analysisSemantic proximity Read

Association of loneliness, social isolation, and neuroticism in Alzheimer’s disease risk: a two-step Mendelian randomization studySemantic proximity Read

The social problems of older adults during the COVID-19 pandemic, a systematic reviewSemantic proximity Read

Brain Multi-Omic Subtypes of Neuroticism reveal molecular signatures linked to Alzheimer’s DiseaseSemantic proximity Read

Stress internalization associated with cognitive decline among older U.S. ChineseSemantic proximity Read

Neurocognitive Impairment After COVID-19: Mechanisms, Phenotypes, and Links to Alzheimer’s DiseaseSemantic proximity Read

Social isolation, loneliness and all-cause dementia: a longitudinal and imaging-genetic study in the UK Biobank cohortSemantic proximity Read

Psychiatric and Cognitive Morbidity Following Moderate and Severe SARS-CoV-2 Infection: A Cohort StudySemantic proximity Read

How executive control and emotional reactivity influence coping strategies in psychiatric patients during the COVID-19 pandemicSemantic proximity Read

Severe COVID-19 induces molecular signatures of aging in the human brainSemantic proximity Read

Lifestyle, Cognitive, and Psychological Factors Associated With a Resilience Phenotype in Aging: A Multidimensional Approach on a Population-Based Sample of Oldest-Old (80+).Semantic proximity Read

Association of psychosocial state with subsequent risk of dementia: a prospective cohort study based on the UK Biobank.Semantic proximity Read