Article

CCT2 prevented β-Catenin proteasomal degradation to sustain cancer stem cell traits and promote tumor progression in epithelial ovarian cancer

2023-04-13

Abstract excerpt

<h4>Background: </h4> Epithelial ovarian cancer (EOC) is featured by rapid progression and dismal outcomes clinically. Chaperonin Containing TCP1 Subunit 2 (CCT2) was identified as a crucial regulator for tumor progression, however, its exact role in EOC remained largely unknown. <h4>Methods: </h4>: CCT2 expression and prognostic value in EOC samples were assessed according to TCGA dataset. Proliferation and mobi...

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Literature Corpus work: 47b81e55-3246-5484-bb7e-1687584e1092
DOI: 10.21203/rs.3.rs-2726690/v1

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