Article

Differential Network Analysis of Longitudinal Gene Expression in Response to Perturbations

2021-09-24

Abstract excerpt

Understanding changes in gene expression under the effects of a perturbation is a key goal of systems biology. A powerful approach to address this goal uses gene networks and describes the perturbation’s effects as a rewiring of each gene’s connections. This approach is known as differential network (DN) analysis. Here, we used DNs to analyze RNA-sequencing time series datasets, focusing on expression changes: (i)...

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Literature Corpus work: 475de17a-2d62-53c0-b47a-b865422a42ba
DOI: 10.1101/2021.09.21.461277

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